Cherrelle Elliot has been betrayed by both family and friends. On the day of her wedding, her fiancé jilts her at the altar and marries her first cousin. She is devastated to find that her family members have accepted the relationship without regard to her feelings when she sees her ex-fiancé, cousin, and their new child being admired at the family reunion. Her grief and embarrassment cause her to leave her home city of New Orleans and move to Houston.

After years away from New Orleans, Cherrelle's grandmother asks her to chair the family reunion committee, but she refuses. Reassigned to New Orleans to work on a new project for her company, she is forced to take a matured look at her family, and Cherrelle realizes that some things have changed. Her grandmother is in the early stages of Alzheimer's, her sister is being abused by her husband, and her father is missing to name a few. The only things that make life in New Orleans bearable are the foods that remind her of the love of her family and an unexpected reunion with Cory, a childhood friend she secretly had a crush on.

Her grandmother's disease forces Cherrelle to take over the family reunion, but plans are interrupted when Hurricane Katrina roars through, causing havoc for the family as members are separated from one another.

Living With No Regrets is a story of how Cherrelle and her family deal with betrayal, forgiveness, family, love, reunion planning, Alzheimer's, and spousal abuse.  Recipes to the meals that routinely bring the family together are included.